Monarch Medical Technologies, the market-leading clinical decision support software committed to the safest insulin dosing, today announced that Linda Beneze has joined the company as its new chief executive officer. Formerly the Chief Executive Officer at Medical Technology Products, Beneze has extensive experience building and leading global high-performance teams with expertise in medical device, clinical trial software, bioinformatics, and data management.
“After an extensive selection process, we are delighted to have Linda Beneze lead the company in an evolving and expanding market of inpatient glycemic control. Linda brings a wealth of experience in improving outcomes and enhancing patient and provider safety, alongside her unique blend of leadership experience,” said Christophe Mallard, managing member of private investment firm Eigen Capital Holdings LLC which controls Monarch Medical Technologies. “Linda shares our commitment to patient safety, passion for improving hospital outcomes, and excitement for our future. We look forward to strong continued growth under her leadership.” read more…
Prior to 1921, little was known about the function of the pancreas, and a diagnosis of diabetes almost invariably led to mortality. As insulin enjoyed wider therapeutic application, patient outcomes dramatically improved, and this was not limited to those with diabetes. read more…
One of the most perplexing concerns with which every hospital executive must grapple is how to stop the loss of money wasted on surgery and other clinical procedures. A recent report published in the Journal of Neurosurgery conducted by the University of California in San Francisco suggested several areas where supplies, and therefore money, were wasted.
The report looked at 58 neurosurgeries performed by 14 different surgeons at UCSF Medical Center. Across the 36 cranial and 22 spinal procedures, the average cost of unused supplies was $653. This represented 13.1 percent of the total cost of surgical supplies. This results in $242,968 per month and $2.9 million per year of wasted resources.
Medical Supplies vs. Personnel Costs
While the amount of hospital resources wasted on medical supplies is relatively easy to calculate, the more insidious expenses – clinical personnel costs – are more difficult to quantify. However, when a Roanoke, Virginia hospital set out to improve patient outcomes by standardizing insulin dosing protocols, the facility discovered substantial savings by mechanizing this process. read more…
For patients with type 1 diabetes, one of the most serious medical emergencies is diabetic ketoacidosis (DKA). It can be life-threatening and, in most cases, is caused by a shortage of insulin.
Glucose is the “fuel” which feeds human cells. Without it, these cells are forced to “burn” fatty acids in order to survive. This process leads to the production of acidic ketone bodies which can cause serious symptoms and complications such as passing out, confusion, vomiting, dehydration, coma, and, if not corrected in a timely manner, even death. High levels of ketones poison the body. read more…
Anyone who has ever entered a phrase in the search box of Google and seconds later received direct links to millions of highly-specific references to that phrase, has experienced the power of algorithms. Algorithms are also used in almost every service and product which requires data computation – social networks such as Facebook, online retailers such as Amazon, smart phones, and WiFi systems, to name a few.
According to an article from the University of Utah Health Sciences Center – “Algorithms are Changing Healthcare”– the next frontier for harnessing the power of data to predict outcomes will be in the delivery of healthcare. This trend towards the use of algorithmically based systems is fundamentally changing the way medicine is (and will be) practiced, and it represents a confluence of engineering, clinical medicine, and physiology. It is also the foundation of Monarch Medical Technologies’ glucose management software – EndoTool.
An Expert on Mathematics and Healthcare
In an effort to shed some light on this medical “mega-trend” of algorithmically-based healthcare, Dr. Geoff Chase, a Distinguished Professor at the University of Canterbury in New Zealand and a member of the medical advisory board of Monarch Medical Technologies, was asked to offer his insights as to how mathematics is affecting medicine.
“Everything I do is about modeling non-linear, dynamic systems,” he noted in a recent interview. “I work to understand the data that govern their behavior and use that knowledge to design models to solve whatever problems they are encountering.
Dr. Chase has applied his engineering expertise among a wide-range of high-profile companies and he has done pioneering work on model-based therapeutics.
“In my opinion, modern healthcare has a ‘manufacturing’ problem, not unlike what I dealt with at General Motors. We need better efficiencies in its delivery and this can only occur when we employ the tremendous advances in computer technology. What I did in my early years – making models for the manufacture of automobiles – I now do in the area of metabolic systems.”
Inducing mild hypothermia in some patients with cardiac arrest and other traumatic events has proven to significantly improve their long-term neurological function. Many experts feel that this is one of the most important advancements in the history of the science of resuscitation. According to Dr. Jonathan Adler, writing in Medscape, patients who have been shown to benefit from induced hypothermia include the following:
- Intubated patients with treatment initiated within 6 hours after cardiac arrest
- Patients able to maintain a systolic blood pressure >90 mm Hg after CPR
- Patients in a coma at the time of cooling
When this therapy is used in critical care or the operating room, glucose management is critical to its efficacy, a fact that is appreciated by Tracey Melhuish, Clinical Practice Specialist Critical Care and Sepsis Coordinator and the person responsible for critical care at the 571-bed Holy Cross Hospital in Florida. In response to the challenges of using induced hypothermia as a critical therapy, Ms. Melhuish chose to use EndoTool, a glucose management software for these vulnerable patients.
What Causes Renal Failure?
Kidneys can be injured by a number of reasons. In the United States alone, more than 26 million people are estimated to have Chronic Kidney Disease (CKD), although most don’t know it because early signs are often missed.
“While diabetes is the leading cause of kidney failure that does not mean that everyone with diabetes will develop CKD severe enough to require renal replacement therapy.” said Dr. Burgess, founder of the EndoTool Glucose Management System. Irrespective of the cause of CKD or Acute Kidney Disease (AKD), the clearance of insulin from the body is altered when the patient has kidney dysfunction leading to difficult insulin management problems when intravenous insulin is used to control a patient’s elevated blood glucose level.
Insulin Stacks in Patients with Any Decrease in Kidney Filtration
“With kidney dysfunction, insulin tends to ‘stack,’” Dr. Burgess noted. “Typically, the half-life of IV administered insulin is five to six minutes. This means that if a change is made in the insulin infusion rate, it takes about roughly 20 minutes for the insulin concentration in body fluids to reach equilibrium at the new infusion rate. By understanding the physiology insulin metabolism, the physician can better adjust the next action required to treat an elevated glucose and avoid hypoglycemia.”
“A major factor that affects intravenous insulin dosing is Estimated Residual Extracellular Insulin (EREI) – a new term in medicine. EREI is the term applied to the excess insulin activity that occurs following a decrease in the insulin infusion that is strongly related to kidney filtration. Without accounting for EREI, excess insulin occurs and can result in an undesirable decrease in the blood sugar level.”
“In a healthy patient, the insulin concentration equilibrium is established quickly following changes in the insulin infusion rate. However, in a patient with advanced kidney dysfunction, it might take an hour or more for this to happen. Thus an insulin rate decrease in patients with kidney dysfunction results in more residual insulin activity than the physician intended.”
“Because the majority of insulin is excreted by the kidneys, for patients with kidney dysfunction it is critical that adjustments in dosing occur on a timely and accurate basis. One dosing regimen does not fit all patients and must be adjusted for the many clinical parameters that affect insulin metabolism– including kidney filtration.”
By Stuart Long, CEO of Monarch Medical Technologies
During my career in healthcare, I have worked for many companies that have claimed to save lives. I was originally attracted to Monarch Medical Technologies because it was the first company to truly have that kind of impact. The value our products provide for our customers is measurable from the first dose of insulin, and the outcomes that our customers publish are ground breaking.
Recently, there have been product announcements from companies in the glucose management space promoting new tools to “predict” hypoglycemia. There is a big difference between “those products” which market hypoglycemia’s predictive ability and the EndoTool technology. EndoTool not only predicts changes in glucose levels, it also takes the next step in terms of treatment by adjusting insulin dosing recommendations for every single blood glucose (BG) check. This capability is starting to appear in all care segments, yet we feel it is especially important in an inpatient environment. read more…
Advances in computer technology have brought about an ever – expanding list of tasks, which had previously required the manual ‘human touch,’ and now are programmed to automatically occur. The high profile examples of this phenomenon are self-driving cars, thermostats that adjust themselves based on the time of day, and the amazing interconnectivity of the “Internet of Things.” Computer guided systems can also dramatically improve the effectiveness of life-or-death medical tasks in a hospital such as blood glucose management.
According to a recent, seven-year study of patients who require IV insulin infusion, the use of algorithmically based computerized systems can optimize the timing of blood glucose checks and dosing, thereby improving patient outcomes. This research, conducted in the Vidant Medical Center, a 900-bed, tertiary care teaching hospital located in Greenville, North Carolina, evaluated the impact of EndoTool ™ Electronic Glycemic Management System and the results were remarkable.
The recent controversies at the National Institute of Health (NIH) Clinical Center are every hospital administrator’s worst nightmare. According to a June 2, 2016 article in the Wall Street Journal a Bethesda, Maryland hospital, recognized for its cutting-edge medical research, has an unsafe pharmacy dosing program for patients.
In 2015, Federal Drug Administration (FDA) inspectors found what they termed “serious manufacturing problems” with the hospital pharmacy. Then, in April 2016, an outside group of experts concluded that the two laboratories drug production for clinical studies on patients did not comply with safety standards.