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Evaluation of Glucose Management Software in Critically Ill Patients with Hyperglycemic Crises

Objective

This retrospective review examines the safety and effectiveness of a computerized glucose management system (EndoTool) for critically ill diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic states (HHS) patients.

Setting

1,041-bed non-profit tertiary care and academic medical center.

Results
  • With an initial blood glucose >300 mg/dL, mean rate of blood glucose reduction was 87 mg/dL/hour, with 84% of patients achieving a rate of at least 50 mg/dL/hour.
  • Incidence of severe hypoglycemia <40 mg/dL was 0.17% of blood glucose measurements and incidence of hypoglycemia <60 mg/dL was 0.79% of blood glucose measurements.
Conclusions

Management of continuous intravenous insulin infusion utilizing a computerized glucose management system (EndoTool) is both safe and effective at lowering blood glucose in DKA and HHS patients, with very minimal risk of hypoglycemia.

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Authors

Maresa Glass, PharmD, BCPS; Kevin Ferguson, PharmD, BCPS; Mark Rumbak, MD.

Source

Presented at Society of Critical Care Medicine Critical Care Congress. Published in Critical Care Medicine, Volume 42, Issue 12, pA1441.

Year

2014

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