• Clinical Evidence

Evaluation of Glucose Management Software in Critically Ill Patients with Hyperglycemic Crises

Setting: 1,041-bed non-profit tertiary care and academic medical center.

Objective

This retrospective review examines the safety and effectiveness of a computerized glucose management system (EndoTool) for critically ill diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic states (HHS) patients.

Setting

1,041-bed non-profit tertiary care and academic medical center.

Results

  • With an initial blood glucose >300 mg/dL, mean rate of blood glucose reduction was 87 mg/dL/hour, with 84% of patients achieving a rate of at least 50 mg/dL/hour.
  • Incidence of severe hypoglycemia <40 mg/dL was 0.17% of blood glucose measurements and incidence of hypoglycemia <60 mg/dL was 0.79% of blood glucose measurements.

Conclusions

Management of continuous intravenous insulin infusion utilizing a computerized glucose management system (EndoTool) is both safe and effective at lowering blood glucose in DKA and HHS patients, with very minimal risk of hypoglycemia.

Objective

This retrospective review examines the safety and effectiveness of a computerized glucose management system (EndoTool) for critically ill diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic states (HHS) patients.

Setting

1,041-bed non-profit tertiary care and academic medical center.

Results
  • With an initial blood glucose >300 mg/dL, mean rate of blood glucose reduction was 87 mg/dL/hour, with 84% of patients achieving a rate of at least 50 mg/dL/hour.
  • Incidence of severe hypoglycemia <40 mg/dL was 0.17% of blood glucose measurements and incidence of hypoglycemia <60 mg/dL was 0.79% of blood glucose measurements.
Conclusions

Management of continuous intravenous insulin infusion utilizing a computerized glucose management system (EndoTool) is both safe and effective at lowering blood glucose in DKA and HHS patients, with very minimal risk of hypoglycemia.

References

Authors

Maresa Glass, PharmD, BCPS; Kevin Ferguson, PharmD, BCPS; Mark Rumbak, MD.

Source

Presented at Society of Critical Care Medicine Critical Care Congress. Published in Critical Care Medicine, Volume 42, Issue 12, pA1441.

Year

2014

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Objective
Setting
Results
Conclusions
References
Objective

This retrospective review examines the safety and effectiveness of a computerized glucose management system (EndoTool) for critically ill diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic states (HHS) patients.

Setting

1,041-bed non-profit tertiary care and academic medical center.

Results
  • With an initial blood glucose >300 mg/dL, mean rate of blood glucose reduction was 87 mg/dL/hour, with 84% of patients achieving a rate of at least 50 mg/dL/hour.
  • Incidence of severe hypoglycemia <40 mg/dL was 0.17% of blood glucose measurements and incidence of hypoglycemia <60 mg/dL was 0.79% of blood glucose measurements.
Conclusions

Management of continuous intravenous insulin infusion utilizing a computerized glucose management system (EndoTool) is both safe and effective at lowering blood glucose in DKA and HHS patients, with very minimal risk of hypoglycemia.

References

Authors

Maresa Glass, PharmD, BCPS; Kevin Ferguson, PharmD, BCPS; Mark Rumbak, MD.

Source

Presented at Society of Critical Care Medicine Critical Care Congress. Published in Critical Care Medicine, Volume 42, Issue 12, pA1441.

Year

2014

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