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Breaking Down Patient-Specific Insulin Dosing: What Hospitals Need to Know

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Dr. Paul Chidester, MD, FACP

Chief Medical Officer, Monarch Medical Technologies

When it comes to insulin dosing, precision is everything. Traditional insulin protocols rely on just a few factors – point of care glucose levels, weight, and sometimes insulin sensitivity, to determine dosing. But managing insulin needs is far more complex than that.

EndoTool creates a personalized insulin dosing model based on multiple clinical characteristics unique to each patient instead of using one-size-fits-all calculations.

The result- unmatched safety, fewer complications and better outcomes for patients.

Let’s break down the factors that EndoTool considers and why they matter.

The Key Factors in Patient-Specific Insulin Dosing

EndoTool factors in a wide range of patient-specific data:

  1. Point of Care Glucose Value: The starting point for any insulin calculation.
  2. Diabetes Type: Patients without diabetes are more insulin-sensitive than those with diabetes, and even among those with diabetes, Type 1 patients typically require lower doses than Type 2.
  3. Patient Characteristics: Age, sex, height, and weight all influence insulin sensitivity.
  4. Kidney Function (Serum Creatinine & eGFR): EndoTool precisely calculates residual insulin levels to prevent excessive insulin administration, significantly reducing the risk of hypoglycemia. This is especially effective in patients with kidney failure or reduced renal function, where insulin has a prolonged half-life.
  5. Hemoglobin A1C (HbA1c) – A reflection of long-term blood sugar control. A higher A1C, especially over 7, suggests greater insulin resistance, influencing dosing decisions.
  6. Steroid Use – Steroids increase insulin resistance. EndoTool increases starting insulin dose recommendations when steroids have been administered within the past 24 hours.
  7. Dosing Mode (Hyperglycemia, DKA, or HHS Treatment) – Different conditions require different insulin strategies. EndoTool adapts doses to meet the specific needs of patients in hyperglycemic crises.

How do These Factors Work Together to Improve Outcomes?

One of EndoTool’s biggest advantages is how it adjusts dosing in real time based on changes in patient status.

Kidney Function & Insulin Sensitivity

As kidney function declines (measured by eGFR), insulin stays in the body longer. EndoTool accounts for this by reducing insulin doses for patients with impaired kidney function, significantly lowering the risk of hypoglycemia.

Diabetes Type & Insulin Sensitivity

Insulin needs vary based on diabetes type, with patients who have Type 1 diabetes typically requiring less insulin than those with Type 2, and those without diabetes needing even less. EndoTool accounts for these differences by continuously optimizing insulin dose recommendations, supporting clinicians in making optimal dosing decisions.

Steroid Use & Insulin Resistance

Steroids make the body more resistant to insulin, EndoTool therefore increases the starting insulin dose when steroids have been given, reducing the risk of uncontrolled blood sugar spikes.

Predictive & Adaptive Dosing

EndoTool doesn’t just react-it predicts. With each dosing recommendation, it estimates the next glucose value.

If the actual value is higher than predicted, the system adjusts by increasing the dose. If it’s lower, it reduces insulin accordingly.

Up to four prior glucose values are used in each calculation, ensuring smooth, gradual adjustments rather than abrupt swings in blood sugar levels.

How Patient-Specific Insulin Dosing Makes a Difference:

Traditional insulin dosing methods and other glycemic management solutions rely on limited factors and can lead to suboptimal results.

No other system offers patient-specific insulin dosing like EndoTool. Traditional protocols rely on generalized calculations, and other dosing software and EMR calculators do not adapt in real-time to the unique needs of each patient.

EndoTool continually optimizes insulin dosing by:

  • Virtually eliminating hypoglycemia: Particularly in patients with kidney impairment.
  • Improving glucose stability: By continuously adjusting doses based on real-time patient data.
  • Reducing provider workload: No manual dose adjustments; the system adapts automatically.
  • Enhancing patient safety: By considering multiple factors that impact insulin needs, EndoTool ensures each dose is tailored to the individual.

With EndoTool, insulin dosing isn’t just about numbers. It’s about delivering safe, effective, and patient-specific care.

EndoTool: The Future of Insulin Dosing

With EndoTool, insulin dosing no longer needs to be a one-size-fits-all approach. Instead, it is patient-specific, predictive, and adaptive, ensuring that each patient receives a safe and effective insulin dose.

By leveraging multiple data points, EndoTool optimizes outcomes in a way that neither traditional protocols nor other insulin dosing solutions can achieve.

EndoTool is the only system on the market that continuously adjusts to the unique needs of each patient in real time, making it the only truly patient-specific insulin dosing solution.

See how EndoTool can help your hospital stay ahead of the curve. Let’s talk!

About EndoTool

Made by Monarch Medical Technologies, EndoTool is the only patient-specific insulin dosing system which simplifies the complex task of glycemic management in hospital environments. The recommended dosing is different for each patient based on multiple clinical characteristics. The FDA-cleared platform is utilized in hundreds of hospitals across the United States and is fully integrated with all major electronic medical records. To see how EndoTool can support your health system, get in touch today.

About the author

Dr. Paul Chidester, MD, FACP | Chief Medical Officer, Monarch Medical Technologies

Dr. Paul Chidester is the Chief Medical Officer for Monarch Medical Technologies. After practicing for two decades as a nephrologist, he assumed a senior leadership role at Sentara Healthcare where he led the implementation of computerized insulin dosing software. He is involved with product development and customer engagement at Monarch Medical Technologies where the focus is to provide precision insulin dosing for patients. His key interest is working to further enhance this precision through the use of technologies such as CGM.

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